{"id":7993,"date":"2018-11-23T09:02:10","date_gmt":"2018-11-23T09:02:10","guid":{"rendered":"https:\/\/www.moor.co.uk\/applications\/endothelial-dysfunction\/"},"modified":"2025-04-09T15:12:45","modified_gmt":"2025-04-09T15:12:45","slug":"endothelial-dysfunction","status":"publish","type":"m_applications","link":"https:\/\/www.moor.co.uk\/en-us\/applications\/endothelial-dysfunction\/","title":{"rendered":"Endothelial Dysfunction"},"content":{"rendered":"

The endothelium is the lining of blood vessels of the circulatory system, with a fundamental role in vasodilation. Studies of endothelial Dysfunction are widespread and include a number of areas of both clinical and pre-clinical research. Fundamental to such studies are the techniques of laser Doppler monitoring, imaging and Laser Speckle combined, for example, with pressure cuff challenges, iontophoresis and\/ or skin heating to provide reproducible challenges. The advantage of imaging is that blood flow can be imaged and recorded over an area of interest rather than a single point measurement, thus results are both more reliable and show better reproducibility.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Techniques<\/span><\/td>\nField of study<\/span><\/td>\nReference<\/span><\/td>\n<\/tr>\n
Iontophoresis<\/td>\nRaynaud\u2019s Phenomenon<\/td>\nShepherd et al, 2019<\/td>\n<\/tr>\n
<\/td>\nEthnicity<\/td>\nMaley et al, 2017<\/td>\n<\/tr>\n
<\/td>\nGlaucoma<\/td>\nBukhari et al, 2019<\/td>\n<\/tr>\n
<\/td>\nCardiovascular disease<\/td>\nFrank et al. 2010
\nGeorge et al. 2009
\nJadhav et al. 2007
\nKhan et al. 2008<\/td>\n<\/tr>\n
<\/td>\nDiabetes<\/td>\nBeer et al. 2008
\nFranklin et al. 2008<\/td>\n<\/tr>\n
<\/td>\nPeripheral neuropathy<\/td>\nBrooks et al, 2008<\/td>\n<\/tr>\n
<\/td>\nSystemic sclerosis<\/td>\nGunawardena et al 2007a
\nMurray et al. 2008<\/td>\n<\/tr>\n
<\/td>\nDermal microvascular blood flow<\/td>\nAgarwal et al. 2010<\/td>\n<\/tr>\n
<\/td>\nIdiopathic inflammatory myopathy<\/td>\nGunawardena et al 2007b<\/td>\n<\/tr>\n
Skin heating & Iontophoresis<\/td>\nVascular reactivity<\/td>\nBeed et al, 2009<\/td>\n<\/tr>\n
Heating<\/td>\nVascular reactivity<\/td>\nCasey et al, 2020
\nDel Pozzi et al, 2016
\nMinson et al, 2002<\/td>\n<\/tr>\n
PORH<\/td>\nEndothelial function<\/td>\nYamamoto-Suganuma & Aso, 2009<\/td>\n<\/tr>\n
<\/td>\nEndothelial function<\/td>\nSpaan et al, 2010<\/td>\n<\/tr>\n
<\/td>\nMicrovascular function – CVD<\/td>\nShore et al, 2005<\/td>\n<\/tr>\n
PORH & Heating<\/td>\nEndothelial Function & Ethnicity<\/td>\nPetrofski et al, 2013
\nStrain et al, 2010<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":0,"template":"","tags":[],"class_list":["post-7993","m_applications","type-m_applications","status-publish","hentry"],"acf":[],"yoast_head":"\nEndothelial Dysfunction | Speckle Contrast | Moor Instruments<\/title>\n<meta name=\"description\" content=\"Studies of endothelial dysfunction are widespread and include a number of areas of both clinical and pre-clinical research\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.moor.co.uk\/en-us\/applications\/endothelial-dysfunction\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Endothelial Dysfunction | Speckle Contrast | Moor Instruments\" \/>\n<meta property=\"og:description\" content=\"Studies of endothelial dysfunction are 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