{"id":7916,"date":"2018-11-23T09:04:09","date_gmt":"2018-11-23T09:04:09","guid":{"rendered":"https:\/\/www.moor.co.uk\/applications\/peripheral-autonomic-neuropathy\/"},"modified":"2025-10-10T13:55:42","modified_gmt":"2025-10-10T13:55:42","slug":"peripheral-autonomic-neuropathy","status":"publish","type":"m_applications","link":"https:\/\/www.moor.co.uk\/en-us\/applications\/peripheral-autonomic-neuropathy\/","title":{"rendered":"Peripheral Autonomic Neuropathy"},"content":{"rendered":"

When a stimulus causes backward nerve transmission, vasodilation of the innervated blood vessels occurs; this is the axon reflex, also referred to as the flare response. An impaired axon reflex indicates peripheral neuropathy. In practical terms, when skin is heated (by using the moorVMS-HEAT) or iontophoresed (by using the moorVMS-ION) with acetylcholine over a well defined area, microvascular blood flow also increases in the surrounding skin (as well as at the site stimulated). Laser Doppler monitoring (moorVMS-LDF) is used to assess the magnitude and time course of the vasodilation, and additional information on the flare area can be obtained with laser Doppler (moorLDI2) and Speckle imaging (moorFLPI-2).<\/p>\n","protected":false},"featured_media":0,"template":"","tags":[],"class_list":["post-7916","m_applications","type-m_applications","status-publish","hentry"],"acf":[],"yoast_head":"\nPeripheral Autonomic Neuropathy | Laser Speckle | Moor Instruments<\/title>\n<meta name=\"description\" content=\"Laser Doppler monitoring is used to assess the magnitude and time course of the vasodilation, and additional information on the flare area can be obtained with laser Doppler and Speckle imaging.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.moor.co.uk\/en-us\/applications\/peripheral-autonomic-neuropathy\/\" \/>\n<meta property=\"og:locale\" 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