MBF3D

Tissue blood flow monitoring

  • In a nutshell, moorFLPI-2 is the most user-friendly system for studying cerebral blood flow regulation in rodents.

    Chia-Yi (Alex) Kuan, MD, PhD
    Emory University School of Medicine

  • We have found Moor equipment to be extremely dependable and innovative.

    Dean L. Kellogg, Jr., MD, Ph.D
    University of Texas Health Science Center

  • We can't recommend Moor instruments highly enough. The technology is at the cutting edge and the support second to none.

    Paul Sumners, PhD
    London South Bank University

  • I cannot rate the company or the staff highly enough.

    Jim House, PhD
    University of Portsmouth

  • Laser Doppler Imager is a standard accurate method we now use in our cerebral blood flow and brain perfusion in our laboratory.

    Momoh A. Yakubu, PhD
    Texas Southern University

  • Moor Instruments have consistently provided excellent help and support for my research.

    Kim Gooding, PhD
    University of Exeter Medical School

  • It goes without saying that the company's imaging technology itself is superb!

    Gourav Banerjee
    Leeds Beckett University

  • I expect to be using Moor Instrument’s technology for many years to come!

    Faisel Khan, PhD
    Ninewells Hospital & Medical School

This system has now been superseded by the moorVMS-LDF, for full details please click here.

Unfortunately optic probes for this product are no longer manufactured.

The MBF3D was the first system to offer dual channel monitoring to allow customers to easily compare blood flow at two sites simultaneously. The monitor featured a unique self contained design with graphic display, data memory, in built colour plotter and easy PC / analogue connections. A highly advanced solution, for the time, that would still compete today.

We are able to support this system with calibration fluid, PC software, plotter paper and pens ONLY. If you are not sure of the safety or functionality of the system then our technicians can help with an ‘MBF3D™ check’. The MBF3D ceased manufacture in 1993 so some internal components are no longer available. We can advise on a case by case basis.

This system has now been superseded by the moorVMS-LDF, for full details please click here.

The following products are AVAILABLE TO BUY ONLINE and work with the MBF3D


This system has now been superseded by the moorVMS-LDF, for full details please click here.

The list below contains a selection of references citing use of our laser Doppler monitors. The list below is a small selection. Please contact us for reference lists on your chosen subject.


Ajcharanukul, O. et al., 2007.
Effects of potassium ions on dentine sensitivity in man.
Archives of oral biology, 52(7), pp.632–9.

Akerman, S. & Goadsby, P.J., 2005.
Topiramate inhibits cortical spreading depression in rat and cat: impact in migraine aura.
Neuroreport, 16(12), pp.1383–7.

Alkayed, N.J. et al., 1998.
Gender-linked brain injury in experimental stroke.
Stroke; a journal of cerebral circulation, 29(1), pp.159–65; discussion 166.

Al-Rawi, P.G. & Kirkpatrick, P.J., 2006.
Tissue oxygen index: thresholds for cerebral ischemia using near-infrared spectroscopy.
Stroke; a journal of cerebral circulation, 37(11), pp.2720–5.

Attar, F. et al., 2007.
Perioperative changes in the microcirculation in feet after foot and ankle surgery.
The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons, 46(4), pp.238–41.

Booker, P.D. et al., 1999.
Angiotensin II concentrations and gut mucosal perfusion in infants undergoing cardiopulmonary bypass.
Journal of cardiothoracic and vascular anesthesia, 13(4), pp.446–50.

Booker, P.D., Romer, H. & Franks, R., 1996.
Gut mucosal perfusion in neonates undergoing cardiopulmonary bypass.
British journal of anaesthesia, 77(5), pp.597–602.

Conesa, E.L. et al., 2001.
N-acetyl-L-cysteine improves renal medullary hypoperfusion in acute renal failure. American journal of physiology.
Regulatory, integrative and comparative physiology, 281(3), pp.R730–7.

Corbett, S., McCarthy, I. & Batten, J., 1999.
Nitric oxide mediated vasoreactivity during fracture repair.
Clinical orthopaedics and related research, pp.247–253.

Drummond, P.D., 2011.
Inflammation contributes to axon reflex vasodilatation evoked by iontophoresis of an α-1 adrenoceptor agonist.
Autonomic neuroscience : basic & clinical, 159(1-2), pp.90–7.

Evans, R.G., Madden, a C. & Denton, K.M., 2000.
Diversity of responses of renal cortical and medullary blood flow to vasoconstrictors in conscious rabbits.
Acta physiologica Scandinavica, 169(4), pp.297–308.

Falk, S.J. et al., 1994.
ONCOLOGY BWl2C perturbs normal and tumour tissue oxygenation and blood.
32, pp.210–217.

Ghafouri, S., Hajizadeh, S. & Mani, A.R., 2011.
Enhancement of insulin-induced cutaneous vasorelaxation by exercise in rats: A role for nitric oxide and K(Ca2+) channels.
European journal of pharmacology, 652(1-3), pp.89–95.

Heidarianpour, A., 2010.
Does detraining restore influence of exercise training on microvascular responses in streptozotocin-induced diabetic rats?
Microvascular research, 80(3), pp.422–6.

Hern, S. et al., 1999.
Control of cutaneous blood vessels in psoriatic plaques.
The Journal of investigative dermatology, 113(1), pp.127–32.

Horváth, B. et al., 2010.
Hypersensitivity to thromboxane receptor mediated cerebral vasomotion and CBF oscillations during acute NO-deficiency in rats.
PloS one, 5(12), p.e14477.

Hsu, T.L. et al., 2008.
Effects of angiotensin II on flux rise time in rats (a time index of laser Doppler flowmetry) and its relation with microvascular structures.
Microvascular research, 75(2), pp.211–6.

Hungerhuber, E. et al., 2006.
Simultaneous bilateral laser Doppler fluxmetry and electrophysiological recording during middle cerebral artery occlusion in rats.
Journal of neuroscience methods, 154(1-2), pp.109–15.

Mohagheghi, F. et al., 2011.
The neuroprotective effect of olive leaf extract is related to improved blood-brain barrier permeability and brain edema in rat with experimental focal cerebral ischemia.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(2-3), pp.170–5.

Påhlsson, H.-I., 2007.
Methodological aspects of toe blood pressure measurements for evaluation of arterial insufficiency in patients with diabetes.
N/A

Richter, F. et al., 2010.
The relationship between sudden severe hypoxia and ischemia-associated spreading depolarization in adult rat brainstem in vivo.
Experimental neurology, 224(1), pp.146–54.

Sheu, W.H.-H. et al., 2011.
Microdialysis combined blood sampling technique for the determination of rosiglitazone and glucose in brain and blood of gerbils subjected to cerebral ischemia.
Journal of pharmaceutical and biomedical analysis, 54(4), pp.759–64.

Soo-ampon, S., 2003.
The sources of laser Doppler blood-flow signals recorded from human teeth.
Archives of Oral Biology, 48(5), pp.353–360.

Tomita, Y. et al., 2011.
Long-term, repeated measurements of mouse cortical microflow at the same region of interest with high spatial resolution.
Brain research, 1372, pp.59–69.

Vol, B., 1996.
Pergamon DOPPLER BLOOD-FLOW SIGNALS RECORDED FROM. Science, 41(1), pp.97–103. Vongsavan, N. & Matthews, B., 1993. SOME ASPECTS OF THE USE OF LASER DOPPLER FLOW METERS FOR RECORDING TISSUE BLOOD FLOW.
Experimental Physiology, pp.1–14.

Vongsavan, N. & Matthews, B., 2007.
The relationship between the discharge of intradental nerves and the rate of fluid flow through dentine in the cat.
Archives of oral biology, 52(7), pp.640–7.

Wanachantararak, S., Vongsavan, N. & Matthews, B., 2011.
Electrophysiological observations on the effects of potassium ions on the response of intradental nerves to dentinal tubular flow in the cat.
Archives of oral biology, 56(3), pp.294–305.

Zerari-Mailly, F. & Braud, A., 2012.
Glutamate control of pulpal blood flow in the incisor dental pulp of the rat. European Journal of …, 1.
Eur J O, pp.402–7.