The moorVMS-PRES™ system offers full flexibility to automate pressure cuff protocols. Use either standard, pre-defined protocols or user defined operation to create your own protocol. Full flexibility is allowed to define baseline, target pressure, hold period, deflation rate and post deflation measurements. Coupled with moorVMS-LDF laser Doppler and moorVMS-PC software a complete solution is offered for measurement, protocol automation, analysis and reporting.

Toe pressure (TP) measurements are a useful tool in the diagnosis of peripheral artery disease (PAD) and the assessment of limb ischaemia. TP measurements (using laser Doppler to detect flow return) are particularly useful in patients with non-compressible tibial arteries or other conditions in which calcified arteries occurs. The system is equally useful for measurement of systolic pressure of any digit. The moorVMS-PRES™ system provides automated cuff control – inflation to supra-systolic pressure with slow, automatic linear deflation (at a user defined pre-set rate) thus enabling detection of the reperfusion pressure. The laser Doppler probe is placed distal to the cuff and run the moorVMS-PRES™ protocol. The combination of dedicated hardware and software provides you with the ultimate tool for rapid, simple and accurate TP measurements.

Post Occulsive Reactive Hyperaemia (PORH), the increase in microvascular blood flow following arterial occlusion, can be assessed using the non-invasive laser Doppler technique. Following release of the arterial occlusion there is a marked transient increase in microvascular blood flow to the ischaemic tissues. PORH can be measured using the moorVMS-PRES™ system: simply select the appropriate cuff, place the laser Doppler probe distal to it, and run the moorVMS-PRES™ PORH pre-defined protocol. Alternatively protocols can be written which exactly match user requirements for individual experimental conditions including target pressure and hold times - the user is in no way limited to pre-defined protocols. Dedicated moorVMS-PC™ software enables rapid report generation following PORH and includes, but is not limited to, Resting flux, Time to resting flux level, Maximum flux during reactive hyperaemia and Time to maximum flux.

Limb pressure (LP). There are many Clinical and Research reasons for taking Limb Pressure measurements. The moorVMS-PRES™ system is designed to automate control of the cuff during such pressure measurements. A range of cuff sizes are available to suit your application and measurement site. Attach the laser Doppler probe distal to the cuff. Run the moorVMS-PRES™ protocol and let the automated inflation, hold, deflation program run whilst the moorVMS-PC™ software provides live data recording. The dedicated software enables rapid generation of Reports and automatic pressure calculations.

Skin Perfusion pressure (SPP). Determination of the optimum level for amputation and the determination of levels of ischaemia in patients with peripheral artery disease (PAD) are made simple when Skin Perfusion Pressure is measured using the moorVMS-PRES™. Select an appropriate cuff – a VP11sc flat probe is ideal in this situation and will minimise local artefacts caused by the probe itself. Place the laser Doppler probe under the appropriate size cuff and run the pre-set protocol. The moorVMS-PRES™ will automatically inflate the cuff to a pre-defined level, followed by a controlled slow release of pressure, thus enabling the SPP to be accurately and simply recorded. The dedicated moorVMS-PC™ software generates a report detailing the SPP measurement.

Pulse Volume (PV) measurements reflect arterial pulsatility and are a useful initial test in patients with suspected peripheral artery disease (PAD). In addition PV can also be used as a predictor for critical limb ischaemia and amputation. The moorVMS-PRES™ enables controlled, sensitive and reproducible PV measurements in just a few minutes.

Ankle/Brachial Pressure Index (ABPI) and Toe Brachial Pressure Index (TBPI) are the ratio of systolic blood pressure in the lower legs (ankle or toe) to the systolic pressure in the arms and can be used to assess vascular status. In particular lower pressure in the leg compared to the arm can be used as a predictor for arterial occlusion. Using the moorVMS-PRES™ and moorVMS-PC™ software ABPI and TBPI measurements can be performed simply and result in automatically generated analysis reports. The laser Doppler probes and cuffs are placed on the limbs and measurements taken with automated inflation, hold and deflation of the cuffs by the moorVMS-PRES™. The automatically generated report enables the user to view the ABPI (or TBPI) in addition to related statistics such as mean toe pressure for each site measured, mean brachial pressure for each site measure, mean TBPI or ABPI for each site measured.

Postrual Vasoconstriction. Venous insufficiency, occurring as a result of calf muscle pump failure and incompetent venous valves, often leads to oedema and also the formation of venous ulcers. An index of postural vasoconstriction is produced when measurements of the percentage change in flux with the leg at heart level, and then dependant are performed. Such measurements are easily performed using the moorVMS-PRES™ and taking limb pressures as described in 2 above.

Custom Protocols. Most of the moorVMS-PRES™ protocols follow a common theme –Resting baseline, inflation to target pressure, hold time, deflation (at preset rate) and a post-deflation recording of flux. The moorVMS-PRES™ is a flexible system enabling the user to define individual protocols to suit their individual needs – whilst maintaining a user friendly interface. Further customisation and the inclusion of tissue heating, or iontophoresis, for example is possible with the use of the moorVMS-PC™ software