This section lists the more common questions our customers have about MIC2 Iontophoresis. If you have a question you would like answered that does not appear below then please email us. We are happy to help!
Q. Can the MIC2 be used in stand alone mode?
A. Yes, the current level and time duration for drug delivery is set easily using the front panel of the MIC2. However, when the system is connected to a DRT4 or MoorLDI system enhanced protocols are available allowing a high degree of flexibility in the current control. The DRT4 for example can be programmed for 15 individual periods of variable duration and current delivery. The protocol is 'played' with a single keypress.
Q. Why is multi-period control a benefit?
A. It has been shown that responses to certain vaso-active drugs is enhanced when the delivery is spread over 3 or more periods, rather than one individual delivery. It is far better if such a protocol is controlled automatically to ensure reproducibility of the test.
Q. How is the MIC2 powered?
A. The MIC2 is powered by four regular AA batteries.
Q. Is the MIC2 safe in use?
A. Yes. We take patient safety extremely seriously. IRB (USA) and REB (Canada) must be sought before the system can be used in these markets. Please direct any questions to our sales team!
Q. Why does MIC2 offer ultra low current setup?
A. Ultra low current doses are available to avoid the 'Galvanic Effect'. This is a current effect that can cause an increase in tissue blood flow when substances that are non vasoactive (such as water) are delivered. When it is important to avoid this effect we recommend current settings of less than 50 microamps are used - MIC2 will deliver down to 0.1 microamps.
Q. Which drugs are typically iontophoresed?
A. Laser Doppler & Iontophoresis is used for test purposes (not for treatments). Please refer to Theory Download (right) for full information.
Typical drugs and uses are:
Acetylcholine chloride for assessment of endothelial function (when LD is used at the site of ionto); it is also used for the assessment of peripheral autonomic neuropathy (when LD is used away from the site of ionto to assess the axon reflex flare);
Sodium nitroprusside for the assessment of smooth muscle function;
Histamine as an alternative to the prick test and to test small fibre neuropathy;
Anti-Histamine drugs to test their effect on the flare due to histamine injection (e.g. Nedocromil sodium, frusemide bumetanide).