Applications

Peripheral Arterial Occlusive Disease (PAOD)

Peripheral Arterial Occlusive Disease (PAOD) is a disease state and also includes peripheral vascular disease (PVD) or peripheral arterial disease (PAD). For many years laser Doppler has been used in the assessment of PAOD (Walberg et al, 1995, Rossi & Carpi, 2004) and PAOD related diseases. The following provides a brief overview of some of the specific tests and Applications for laser Doppler in PAOD, PVD and PAD.

Ankle brachial pressure index (ABPI)

Some patients presenting with PVD are asymptomatic, and an abnormal ABPI is the first indication of the presence of disease. For patients with PAOD an ABPI of 0.5 – 0.9 is commonly used to define those with disease (Urbančič-Rovan, 2006). Using the moorVMS-LDF, moorVMS-PRES, probes, cuffs and dedicated PC software with automatic ABPI calculation this test is made simple! Click here for more on the ABPI test.

ABPI being quickly and easily performed with the moorVMS-LDF, moorVMS-PRES, cuff and probe.

Laser Doppler monitoring

Choose laser Doppler monitoring for the monitoring of blood flow in skin and a single, or multiple points, on patients with PAOD (Rossi & Carpi, 2004). Choose probes with temperature monitoring (VP1T) to enable simultaneous monitoring of blood flow and temperature.

Above is the blood flow monitor, the moorVMS-LDF, with a range of probes. The most popular probe for studying skin microvascular blood flow in PAOD is the skin probe with temperature, the VP1T.

Post-occlusive reactive hyperaemia (PORH)

In diabetic patients, and others with calcified or hardened arteries, in which ABPI may not provide an accurate result, PORH has been measured and suggested as a possible predictor of early PVD - at least in the Type I Diabetes group (Jaffer et al, 2008).

PORH being quickly and easily performed with the moorVMS-LDF, moorVMS-PRES, cuff and probe.

References

Jaffer U., Aslam M., Standfield N. 2008 Impaired Hyperaemic and Rhythmic Vasomotor Response in Type 1 Diabetes Mellitus Patients: A Predictor of Early Peripheral Vascular Disease. European Journal of Vascular and Endovascular Surgery, 35, pp 603-606

Rossi M. and Carpi A. 2004 Skin microcirculation in peripheral arterial obliterative disease. Biomedicine & Pharmacotherapy 58, pp 427–431

Urbančič-Rovan V., Bernjak A., Stefanovska A., Ažman-Juvan K., Kocijančič A. 2006 Macro- and microcirculation in the lower extremities - Possible relationship. Diabetes Research and Clinical Practice, 73, pp 166–173

Wahlberg E., Olofsson P., Swedenborg J., Fagrell B. 1995 Changes in Postocclusive Reactive Hyperaemic Values as Measured with Laser Doppler Fluxmetry after Infrainguinal Arterial Reconstructions. Eur J Vasc Endovasc Surg, 9, pp 197-203

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